Peptide Database

Peptide NameNL9-F11A

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC58H83N15O15S

DescriptionStandard

        ACWWAGIKQEA
    

Molecular Weight1262.44 Da

Isoelectric Point (pI)6.04

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0193

GRAVY Index-0.06

Hydrophobic Moment 0.22

Boman Index0.23

Instability Index80.46

Aliphatic Index 62.73

Aromaticity 0.1818

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 492.31

LogP -2.38

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 38.0

Heavy Atoms 89.0

Ring Count 4.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396224 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Integrase inhibition

Activity245±13 μM

MethodIC50

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