Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length556 amino acids

Chemical FormulaC2738H4272N752O830S24

DescriptionStandard

        MAIGYFLLVGDKTTCGGQIITGDHTMTFNGRATAREGDTVTCGKHLGTYMIVGGVSDVFDMGRKLAGTLDSVSTCPCRARFINSEMDSYEKQEQPNNRATTPVNMAVQNFSSPMEEARNVQPAPPVTKAPPIPVFAKSCLRGKGCTDAGTEAEPADNFGRMAIYQVPSSPTPVTPPKPELPPQGEKQPPEPDKPQDKKLPWYKRWFRSDEDKAEAAATAVAATARSAVAEGETLVMRYIGGGAISAGRWLAAPNPVTVGLMGLFYSPKLNEGEEDYLTPYRLSQIAEQYGKAPTRVRFRWIRDEKSGRMTVQGYHVSPEGGLDKVPVRMMTLNRTTGNYEFWEPGEYRPIILWMPNEQEFKVPAHTGNEEQPFIPSQITVLPIPEKVGSDIESLPMPEEKDFRDYILILPVPNMPPVYVYLSKPPVKPLEVGEYQDLAGRSRNDGLDIDHIPSQAALKIYLIERYGELDSGVLKNILENSVCIAVSRWVHQKYSETYGGRNTPTKRIRDASDLKAAVDSNFDAMTPGLKEEGYTDSQLNNARKDLHKFNQEKGWYR
    

Molecular Weight61773.31 Da

Isoelectric Point (pI)5.85

Net Charge (pH 7.0)-5.87

Net Charge (pH 7.4) -6.71

Charge Density (pH 7.0) -0.0105

GRAVY Index-0.56

Hydrophobic Moment 0.67

Boman Index-0.04

Instability Index52.54

Aliphatic Index 68.94

Aromaticity 0.0845

Extinction Coeff. Reduced 78270.00

Extinction Coeff. Oxidized 78645.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007323 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus laumondii subsp. clarkei [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperWhole-genome-based revisit of Photorhabdus phylogeny: proposal for the elevation of most Photorhabdus subspecies to the species level and description of one novel species Photorhabdus bodei sp. nov., and one novel subspecies Photorhabdus laumondii subsp. clarkei subsp. nov. PMID29877789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29877789/