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MYP_135652
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Basic Information
Coagulation factor VIIa Recombinant Human
Antimicrobial
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
Standard
406 amino acids
C1972H3076N560O597S28
Standard
Sequence
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
Physicochemical Analysis
45078.73 Da
6.09
-5.33
-6.57
-0.0131
-0.31
0.80
-0.00
45.79
77.29
0.0813
61880.00
63380.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010516 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Mus musculus [Animal]; Bos taurus [Animal]
Coagulation factor
9606;10090;9913
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Coagulation factor replacement Enzyme replacement
Evidence URLhttps://webs.iiitd.edu.in/raghava/thpdb2/display_thppid.php?details=Th1246
RECORD: Rec_0087825 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Coagulation factor
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Coagulation factor replacement Enzyme replacement
Evidence URLhttps://webs.iiitd.edu.in/raghava/thpdb2/display_thppid.php?details=Th1246
RECORD: Rec_0197364 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Coagulation factor
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Coagulation factor replacement
Evidence URLhttps://webs.iiitd.edu.in/raghava/thpdb2/display_thppid.php?details=Th1246
RECORD: Rec_0328406 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Mus musculus [Animal]; Bos taurus [Animal]
Coagulation factor
9606;10090;9913
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Coagulation factor replacement
Evidence URLhttps://webs.iiitd.edu.in/raghava/thpdb2/display_thppid.php?details=Th1246
RECORD: Rec_0392746 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Bos taurus [Animal]
Coagulation factor
9606; 9913
Structure & Mods
single-chain therapeutic peptide/protein [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Coagulation factor replacement Enzyme replacement