Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC347H568N104O87S8

DescriptionStandard

        MKIHLFFLILLFCVTILPARKRYPEYGSLDLRRECKRSNGRCKNQCLETEIRIAFCIRPGTRCCIH
    

Molecular Weight7845.39 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.18

Charge Density (pH 7.0) 0.1153

GRAVY Index-0.04

Hydrophobic Moment 0.62

Boman Index-0.09

Instability Index64.23

Aliphatic Index 96.06

Aromaticity 0.0909

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3104.37

LogP -24.27

H-bond Donors 119.0

H-bond Acceptors 105.0

Rotatable Bonds 263.0

Heavy Atoms 546.0

Ring Count 11.0

Amide Bonds 68.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0199454 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence