Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide 4

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC24H39N7O7

DescriptionStandard

        VYRT
    

Molecular Weight537.61 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)0.73

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.1832

GRAVY Index-0.57

Hydrophobic Moment 0.90

Boman Index-0.31

Instability Index-53.62

Aliphatic Index 72.50

Aromaticity 0.2500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 252.98

LogP -1.90

H-bond Donors 10.0

H-bond Acceptors 8.0

Rotatable Bonds 15.0

Heavy Atoms 38.0

Ring Count 1.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136151 VERIFIED: YES

Provenance & Taxonomy

OrganismPalmaria palmata [Plant]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity0.14 μM

MethodIC50

RECORD: Rec_0189746 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)