Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC225H347N65O72S6

DescriptionStandard

        HPGDAQGPDSCNHRGGLCRVGTCVSGEYPAQYCFEPIILCCKNLPPATTE
    

Molecular Weight5306.94 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-2.11

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0422

GRAVY Index-0.34

Hydrophobic Moment 0.43

Boman Index0.04

Instability Index40.37

Aliphatic Index 56.60

Aromaticity 0.0600

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2144.13

LogP -26.16

H-bond Donors 76.0

H-bond Acceptors 78.0

Rotatable Bonds 161.0

Heavy Atoms 368.0

Ring Count 11.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299645 VERIFIED: YES

Provenance & Taxonomy

OrganismCyanistes caeruleus [Animal]

FamilyDefensin

Tax ID156563

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/