Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC167H269N49O56S2

DescriptionStandard

        KCNTATCVTQRLADFLVRSSGNIGAIYSPTNVGSNTY
    

Molecular Weight3923.35 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.10

Hydrophobic Moment 0.68

Boman Index0.04

Instability Index24.32

Aliphatic Index 73.78

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1727.23

LogP -24.77

H-bond Donors 63.0

H-bond Acceptors 60.0

Rotatable Bonds 125.0

Heavy Atoms 274.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188327 VERIFIED: YES

Provenance & Taxonomy

OrganismPhilomachus pugnax [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)