Peptide Database

Peptide NameCD70

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length193 amino acids

Chemical FormulaC930H1494N276O266S10

DescriptionStandard

        MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP
    

Molecular Weight21118.15 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)5.05

Net Charge (pH 7.4) 4.34

Charge Density (pH 7.0) 0.0262

GRAVY Index0.00

Hydrophobic Moment 0.64

Boman Index0.06

Instability Index55.19

Aliphatic Index 96.99

Aromaticity 0.0570

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8608.06

LogP -109.50

H-bond Donors 308.0

H-bond Acceptors 288.0

Rotatable Bonds 679.0

Heavy Atoms 1482.0

Ring Count 34.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353381 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted N-linked glycosylation of asparagine residues at positions 63 and 170; disulphide bond formation between cysteine residues at positions 133 and 151

Bio-Activity Profile

Function

Immunomodulatory Signaling peptide

TargetCD27 (Human)