‹ ›
MYP_135521
← PREVIOUS NEXT → BACK
Basic Information
Tigerinin-1 (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
11 amino acids
C61H94N14O14S3
Standard
Sequence
FCTMIPIPRCY
Physicochemical Analysis
1343.68 Da
8.06
0.74
0.51
0.0672
0.82
0.32
0.28
26.64
70.91
0.1818
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
439.10
-1.20
17.0
18.0
37.0
92.0
4.0
10.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0327262 VERIFIED: YES
Provenance & Taxonomy
Hoplobatrachus tigerinus [Animal]
Structure & Mods
disulfide-constrained peptide with intramolecular loop [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus MT 166
20 μg/mL
MIC
PMID11031261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11031261/
RECORD: Rec_0368261 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
disulfide-constrained peptide with intramolecular loop [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-10
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antibacterial
Escherichia coli W 160.37
40 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina. PMID11031261
RECORD: Rec_0417799 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0422410 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
2-10
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis
30 μg/mL
MIC
PMID11031261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11031261/
RECORD: Rec_0423236 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
disulfide-constrained peptide with intramolecular loop [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-10
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Cytotoxic
MCF-7
29.6 μM
IC50
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina. PMID11031261
FIRST PREV 1 ... 5 6 7
Showing 5 records · Page 7 of 7