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MYP_135521
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Basic Information
Tigerinin-1 (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
11 amino acids
C61H94N14O14S3
Standard
Sequence
FCTMIPIPRCY
Physicochemical Analysis
1343.68 Da
8.06
0.74
0.51
0.0672
0.82
0.32
0.28
26.64
70.91
0.1818
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
439.10
-1.20
17.0
18.0
37.0
92.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0136355 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2-10
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
PC3
49.7 μM
IC50
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
RECORD: Rec_0136463 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2-10
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
cancer cells, including A549
27.4 μM
IC50
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
RECORD: Rec_0156663 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2-10
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
yeast Saccharomyces cerevisiae ATCC 8530
80 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
RECORD: Rec_0178320 VERIFIED: YES
Provenance & Taxonomy
Hoplobatrachus tigerinus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis
PMID11031261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11031261/
RECORD: Rec_0195328 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2-10
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Bacillus subtilis
30 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
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