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MYP_135518
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Basic Information
Longicornsin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
47 amino acids
C231H357N69O58S11
Standard
Sequence
DFGCGQGMIFMCQRRCMRLYPGSTGFCRGFRCMCDTHIPLRPPFMVG
Physicochemical Analysis
5381.45 Da
8.98
3.79
3.45
0.0806
0.05
0.73
0.03
54.27
39.36
0.1277
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2008.54
-18.73
77.0
74.0
170.0
369.0
11.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0311029 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
PaperPubMed PMID: 20027626 PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0320819 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit erythrocytes
200 μg/mL
Hemolysis
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0338025 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
PaperPubMed PMID: 20027626 PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0365092 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922 or 23A or 27A
3.2-6.4 μg/mL
MIC
PaperA novel defensin-like peptide from salivary glands of the hard tick, Haemaphysalis longicorn
RECORD: Rec_0372061 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 15A
1.6 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
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