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MYP_135518
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Basic Information
Longicornsin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
47 amino acids
C231H357N69O58S11
Standard
Sequence
DFGCGQGMIFMCQRRCMRLYPGSTGFCRGFRCMCDTHIPLRPPFMVG
Physicochemical Analysis
5381.45 Da
8.98
3.79
3.45
0.0806
0.05
0.73
0.03
54.27
39.36
0.1277
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2008.54
-18.73
77.0
74.0
170.0
369.0
11.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015464 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli 27A
6.4 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0053428 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginoas 7A
0.8 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0088037 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Helicobacter pylori NCTC11637
6.4 μg/mL
MIC
PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0097634 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Longicornsin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperProtein Sci. 2010 Mar;19(3):392-7. | http://www.ncbi.nlm.nih.gov/pubmed/20027626 PMID20027626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20027626/
RECORD: Rec_0098599 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 2592 or 6A or 15A
0.8-1.6 μg/mL
MIC
PaperA novel defensin-like peptide from salivary glands of the hard tick, Haemaphysalis longicorn
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