Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC430H673N107O121S6

DescriptionStandard

        MCTKIIPVLWGCFLLWNLYISSSQTIYPGIKARITQRALDYGVQAGMEMIEQMLRQKNLPDLSGSESLEFLKVDYVNYNFSK
    

Molecular Weight9469.98 Da

Isoelectric Point (pI)7.74

Net Charge (pH 7.0)0.49

Net Charge (pH 7.4) 0.22

Charge Density (pH 7.0) 0.0059

GRAVY Index0.01

Hydrophobic Moment 0.68

Boman Index0.11

Instability Index38.15

Aliphatic Index 98.66

Aromaticity 0.1220

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3693.79

LogP -28.16

H-bond Donors 129.0

H-bond Acceptors 128.0

Rotatable Bonds 315.0

Heavy Atoms 664.0

Ring Count 15.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072235 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyBPI

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence