Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 5L

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC444H740N146O140S8

DescriptionStandard

        MRTLTLLAALLRLALQVQTQSLEETADQVPAQDQPGAEAQDMTISFAGDERSAREASKRPIVCTCRRPWSCRLGERHSGTCRDGQGLIYRLCCRR
    

Molecular Weight10620.04 Da

Isoelectric Point (pI)8.67

Net Charge (pH 7.0)2.55

Net Charge (pH 7.4) 2.18

Charge Density (pH 7.0) 0.0268

GRAVY Index-0.48

Hydrophobic Moment 0.65

Boman Index-0.19

Instability Index56.68

Aliphatic Index 77.16

Aromaticity 0.0316

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4676.99

LogP -56.58

H-bond Donors 173.0

H-bond Acceptors 152.0

Rotatable Bonds 357.0

Heavy Atoms 738.0

Ring Count 9.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414778 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal