Peptide Database

Peptide NameCyclopsychotride A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC124H193N29O35S6

DescriptionStandard

        CGESCVFLPCFIIPGCSCKDKVCYLN
    

Molecular Weight2842.42 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0115

GRAVY Index0.78

Hydrophobic Moment 0.22

Boman Index0.26

Instability Index33.17

Aliphatic Index 82.31

Aromaticity 0.1154

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1003.66

LogP -8.24

H-bond Donors 39.0

H-bond Acceptors 41.0

Rotatable Bonds 88.0

Heavy Atoms 194.0

Ring Count 5.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058707 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0390752 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Tax ID43366

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli