Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC428H686N124O123S15

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAIPFNGVREPEEAGSNDTPVAAHQEMSMESWLMPNHIRQKRQSHLSMCRYCCKCCKGQKGCGMCCRF
    

Molecular Weight10017.76 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.17

Charge Density (pH 7.0) 0.0298

GRAVY Index0.03

Hydrophobic Moment 0.58

Boman Index0.04

Instability Index53.09

Aliphatic Index 68.33

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3944.75

LogP -40.93

H-bond Donors 145.0

H-bond Acceptors 144.0

Rotatable Bonds 333.0

Heavy Atoms 690.0

Ring Count 14.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403842 VERIFIED: NO

Provenance & Taxonomy

OrganismSphaeramia orbicularis [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal