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MYP_135397
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Basic Information
Pseudhymenochirin-1Pb [R8r]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C147H251N39O37
Standard
Sequence
IKIPSFFRNILKKVGKEAVSLIAGALKQS
Physicochemical Analysis
3156.80 Da
10.58
4.76
4.55
0.1641
0.33
0.81
0.11
41.23
124.48
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1245.50
-9.19
43.0
42.0
111.0
223.0
3.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0313956 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Human colon adenocarcinoma HT29
35±5 μM
IC50
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0346438 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 145/08
10 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0347288 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis RP62A
2.5 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0351829 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0370828 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Stenotrophomonas maltophilia B32/1
5 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
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