‹ ›
MYP_135397
← PREVIOUS NEXT → BACK
Basic Information
Pseudhymenochirin-1Pb [R8r]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C147H251N39O37
Standard
Sequence
IKIPSFFRNILKKVGKEAVSLIAGALKQS
Physicochemical Analysis
3156.80 Da
10.58
4.76
4.55
0.1641
0.33
0.81
0.11
41.23
124.48
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1245.50
-9.19
43.0
42.0
111.0
223.0
3.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0168742 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human umbilical vein endothelial cells HUVEC (50% Cell death at 5.6+-0.9 microM, Human erythrocytes
0.9 μM
Hemolysis
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0170114 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli
10 μM
MIC
PaperCharacterization of the host-defense peptides from skin secretions of Merlin's clawed frog Pseudhymenochirus merlini: Insights into phylogenetic relationships among the Pipidae
RECORD: Rec_0171517 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
2.5 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0175883 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans ATCC 90028
80 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0187543 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 127/08
5 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
FIRST PREV 1 ... 3 4 5 6 7 ... 9 NEXT LAST
Showing 5 records on this page · Page 5 of 9