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MYP_135397
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Basic Information
Pseudhymenochirin-1Pb [R8r]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C147H251N39O37
Standard
Sequence
IKIPSFFRNILKKVGKEAVSLIAGALKQS
Physicochemical Analysis
3156.80 Da
10.58
4.76
4.55
0.1641
0.33
0.81
0.11
41.23
124.48
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1245.50
-9.19
43.0
42.0
111.0
223.0
3.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0154973 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 700603
20 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0155304 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549
7.2±1.5 μM
IC50
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0160198 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
80 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0167222 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
10 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0168742 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
D-Arg at position 8 (R8r)
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
>100 μM
HC50
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
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