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MYP_135397
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Basic Information
Pseudhymenochirin-1Pb [R8r]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C147H251N39O37
Standard
Sequence
IKIPSFFRNILKKVGKEAVSLIAGALKQS
Physicochemical Analysis
3156.80 Da
10.58
4.76
4.55
0.1641
0.33
0.81
0.11
41.23
124.48
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1245.50
-9.19
43.0
42.0
111.0
223.0
3.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0124597 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the frog Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25447194 PMID25447194 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25447194/
RECORD: Rec_0127825 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus epidermidis
1.25-2.5 μM
MIC
PaperCharacterization of the host-defense peptides from skin secretions of Merlin's clawed frog Pseudhymenochirus merlini: Insights into phylogenetic relationships among the Pipidae
RECORD: Rec_0128608 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
10 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0131946 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the frog Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells (RBC)
403 μM
LC50
PaperPubMed PMID: 25447194 PMID25447194 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25447194/
RECORD: Rec_0143835 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 12228
40 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
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