Peptide Database

Peptide NameColicin-Ia

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length801 amino acids

Chemical FormulaC3919H6186N1076O1209S9

DescriptionStandard

        MENNTITENTISDGYPTVGDGGQVVLTVWPKGYSPPIYDIWVPPYHGWSKQEWGHNDWIDDTLPPEESKAANRAAEEWAKAYQQEKNKADSYLNDKKQQLSAAYAVLAQSQANHQYIASQLQHINETSPKETLTLQRELANRAVDAARAEIALNTAIVEHLVAESHWSKIMKIYPGTTAAESRERNRLEREKKVEANTLAGSIAQQQHLLNALIADAVVKNTQLEEFNIVDYDPRVISAEQQLVAAQHSLSQAIQDRSVAEQKLAHAQSAYSIANNTAEGRLLANPAAYPYNEILHHSVYGISVQLTISVDNISSLQLLLTQGGTAFSSPITAPTPEGEAIGRSINDLIVDGYNRLRQRLQQRQVEINQATNNINKAQGEVNLANLSVTNNQNTLSQKTQERDGIKSIVSEEVRVKEEREAKVKAAQGQYERAQQALADYKNYGFYGLSQESLLSSSTVLSISAGEGGFASFGSSATATAIRQALISISNKSTQFVVQFGLRSIESAIASRMAVSVGLMSVVFSPSVGEGSDNVPGFFWEKAMIGAVPASMLTLPPDPELRKLAKTVGSIPLNILAVLKHQGNILEFKLIRTPDEYPIGILSAELDSSTGLYQVAIPDVGRTILITPANPPKPNNLPPLVPPIELGTLPLHTGNDVTSDTLPMIEVYPAPESQEGKGWVLVFPEDSGLEAIFVMVSHPPKSEVHKHKHYPPKGVPWSKIVESTKNKGYAKFKPEINIPEIDLDVWKNGEPIAMHLGWKVKKYDYVIGAYNGKETEWVVVKESQGTVHSHPISVQQVNRYLK
    

Molecular Weight88008.11 Da

Isoelectric Point (pI)5.80

Net Charge (pH 7.0)-13.63

Net Charge (pH 7.4) -15.09

Charge Density (pH 7.0) -0.0170

GRAVY Index-0.36

Hydrophobic Moment 0.74

Boman Index0.03

Instability Index42.38

Aliphatic Index 90.12

Aromaticity 0.0687

Extinction Coeff. Reduced 113220.00

Extinction Coeff. Oxidized 113220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224841 VERIFIED: YES

Provenance & Taxonomy

OrganismBudvicia aquatica [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)