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MYP_135252
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Basic Information
PEDF P18
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
34 amino acids
C171H261N45O51
Standard
Sequence
DPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTN
Physicochemical Analysis
3763.17 Da
9.52
1.76
1.55
0.0517
-0.27
0.62
0.00
46.41
65.88
0.1471
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1559.03
-17.58
54.0
53.0
115.0
267.0
8.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000877 VERIFIED: YES
Provenance & Taxonomy
PEDF [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0087478 VERIFIED: YES
Provenance & Taxonomy
PEDF [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0092864 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0158287 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
PEDF
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
Endothelial screening context
PaperSupporting Information for Karagiannis and Popel, PNAS (10.1073/pnas.0803241105) PMID18780781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18780781/
RECORD: Rec_0220390 VERIFIED: YES
Provenance & Taxonomy
PEDF [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
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