Peptide Database

Peptide NameP18

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC98H155N31O30S

DescriptionStandard

        CNPLNGADRRTDSFPRFTVI
    

Molecular Weight2279.53 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0376

GRAVY Index-0.55

Hydrophobic Moment 0.59

Boman Index-0.18

Instability Index32.41

Aliphatic Index 58.50

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1005.81

LogP -12.32

H-bond Donors 36.0

H-bond Acceptors 32.0

Rotatable Bonds 70.0

Heavy Atoms 160.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424355 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli NDM

Activity128 μM

MethodMBC

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