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MYP_135180
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Basic Information
Brevinin-1SN2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C121H197N29O27S3
Standard
Sequence
FMGTALKIAANVLPAAFCKIFKKC
Physicochemical Analysis
2586.23 Da
9.70
3.74
3.50
0.1557
0.97
0.57
0.32
5.22
97.92
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
891.23
-4.26
32.0
34.0
85.0
180.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0320942 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
200 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0349046 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
E. cloacae CGMCC 1.57
100 μM
MIC
PaperIdentification of multiple antimicrobial peptides from the skin of fine-spined frog, Hylarana spinulosa (Ranidae).
RECORD: Rec_0378554 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-positive
Staphylococcus aureus
3.1 μM
MIC
RECORD: Rec_0408587 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 10231
100 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
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