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MYP_135170
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Basic Information
cHLH-p53R
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
39 amino acids
C191H328N62O48S
Standard
Sequence
GARELRRLERELRRLEGGGGGGGKLAALKFKLLWLKLAC
Physicochemical Analysis
4293.10 Da
10.91
5.76
5.53
0.1476
-0.26
1.12
-0.13
69.39
110.26
0.0513
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1809.59
-14.14
68.0
55.0
154.0
302.0
3.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070209 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>64 μM
Hemolysis
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0099521 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-435S
5.7±0.4 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0182356 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
K562
8.2±0.4 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0370226 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0384017 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
MM96L
5.4±0.3 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
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