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MYP_135158
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Basic Information
Dominulin B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
17 amino acids
C89H151N23O23
Standard
Sequence
INWKKIAEIGKQVLSAL
Physicochemical Analysis
1911.29 Da
9.70
1.76
1.55
0.1035
0.27
0.71
0.17
14.12
143.53
0.0588
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
766.48
-4.18
26.0
25.0
67.0
135.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012405 VERIFIED: YES
Provenance & Taxonomy
Polistes dominulus [Animal]
Dominulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Am Soc Mass Spectrom. 2006 Mar;17(3):376-83 | http://www.ncbi.nlm.nih.gov/pubmed/16446098 PMID16446098 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16446098/
RECORD: Rec_0068589 VERIFIED: YES
Provenance & Taxonomy
Polistes dominula [Animal]; Vespa dominula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
8 μg/mL
MIC
RECORD: Rec_0115689 VERIFIED: YES
Provenance & Taxonomy
Polistes dominulus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
2 μg/mL
MIC
PMID16446098 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16446098/
RECORD: Rec_0129769 VERIFIED: YES
Provenance & Taxonomy
Polistes dominulus [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
2 μg/mL
MIC
PMID16446098 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16446098/
RECORD: Rec_0168858 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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