Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length161 amino acids

Chemical FormulaC775H1257N225O249S11

DescriptionStandard

        METQRASLALGRWPLWLLLLGLVVPSASAQALSYREAVLRAVNRLNEQSSEANLYRLLELDPLPKADEDPDTPKPVSFTVKETVCPRTSQQPPEQCDFKENGLVKQCVGTVTLDQSKDQFDINCNEVSVLLGVGVCGCVCECVCVREREREREREREDHSC
    

Molecular Weight18063.34 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-7.46

Net Charge (pH 7.4) -7.92

Charge Density (pH 7.0) -0.0463

GRAVY Index-0.39

Hydrophobic Moment 0.77

Boman Index-0.11

Instability Index35.90

Aliphatic Index 87.08

Aromaticity 0.0435

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7673.25

LogP -82.77

H-bond Donors 271.0

H-bond Acceptors 254.0

Rotatable Bonds 601.0

Heavy Atoms 1260.0

Ring Count 20.0

Amide Bonds 175.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378501 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera musculus [Animal]

FamilyCathelicidin

Tax ID9771

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal