Peptide Database

Peptide NameSarafotoxin-E

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC110H165N27O32S5

DescriptionStandard

        CTCKDMTDKECLYFCHQGIIW
    

Molecular Weight2537.97 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.51

Charge Density (pH 7.0) -0.0567

GRAVY Index-0.07

Hydrophobic Moment 0.38

Boman Index0.07

Instability Index61.21

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 957.51

LogP -6.68

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 82.0

Heavy Atoms 174.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193039 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]

FamilySarafotoxin-E

Tax ID1343144

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0305704 VERIFIED: NO