Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC165H251N43O48S6

DescriptionStandard

        DHYQCVKNGGFCLYSACPVYSKIVGTCYSGKAKCC
    

Molecular Weight3797.41 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0795

GRAVY Index0.04

Hydrophobic Moment 0.36

Boman Index0.10

Instability Index31.15

Aliphatic Index 52.86

Aromaticity 0.1429

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1462.01

LogP -15.92

H-bond Donors 57.0

H-bond Acceptors 58.0

Rotatable Bonds 120.0

Heavy Atoms 262.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085941 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)