Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length438 amino acids

Chemical FormulaC2203H3456N588O610S10

DescriptionStandard

        ANPGFVVRITQAGLDYAHQHGITVLEKELAQLKLPDISGDFRIWHVGKVQYEISRLSLRSFHLPYSRISLVPGVGLQVSISNAFAELDGNWRVKMHFIRDHGSFDLRVENIYIKIHLRLGSDSSGKPTIDTSACSTRISNIRVHFSGKFGWLYNLFHKAIESRFRKILESKVCESVAKSVRSELQPYAQTLPVTARIDAMAGIDYSLVAPPTATAQSLDVDLKGEFFSLAHRSAVPFPPLPLALPPDHDRMVYFGASSYFFNTASFAYHAAGALVFEITNSVIPKGVEFHLNTSTFSAFIPQLEKMYPHMEMKVRLSAPSAPFLNIGPDGLSLKPVVDIQTYAILPNSTLAPLFLLSLVSNVSAVIDVKSGHIVGNLKVGSSSPSPLPAPQVRMLQSIMNVLASSILLPRLNERLAQGFPLPLPDRIQLSNILVGFHQ
    

Molecular Weight48259.23 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)8.20

Net Charge (pH 7.4) 7.09

Charge Density (pH 7.0) 0.0187

GRAVY Index0.12

Hydrophobic Moment 0.72

Boman Index0.14

Instability Index45.89

Aliphatic Index 102.40

Aromaticity 0.0913

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34505.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281399 VERIFIED: NO

Provenance & Taxonomy

OrganismEolophus roseicapilla (Galah cockatoo) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria