Peptide Database

Peptide Name3K + Cecropin A (1-8) + Magainin 2 (1-6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC105H176N26O18

DescriptionStandard

        KKKKWKLFKKIGIGKFL
    

Molecular Weight2090.68 Da

Isoelectric Point (pI)10.85

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.54

Charge Density (pH 7.0) 0.4560

GRAVY Index-0.63

Hydrophobic Moment 0.60

Boman Index-0.17

Instability Index-19.41

Aliphatic Index 91.76

Aromaticity 0.1765

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 752.87

LogP -0.16

H-bond Donors 27.0

H-bond Acceptors 26.0

Rotatable Bonds 79.0

Heavy Atoms 149.0

Ring Count 4.0

Amide Bonds 16.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0378908 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetSalmonella typhimurium KCTC 1926

Activity0.19 μM

MethodMIC

RECORD: Rec_0408470 VERIFIED: YES