Peptide Database

Peptide Nameepigen

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC659H1024N176O189S9

DescriptionStandard

        AAVTVTPPITAQQGNWTVNKTEADNIEGPIALKFSHLCLEDHNSYCINGACAFHHELEKAICRCFTGYTGERCEHLTLTSYAVDSYEKYIAIGIGVGLLLSGFLVIFYCYIRKRCLKLKSPYNVCSGERRPL
    

Molecular Weight14724.83 Da

Isoelectric Point (pI)7.72

Net Charge (pH 7.0)1.16

Net Charge (pH 7.4) 0.54

Charge Density (pH 7.0) 0.0088

GRAVY Index0.02

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index33.44

Aliphatic Index 90.91

Aromaticity 0.1061

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5822.04

LogP -52.83

H-bond Donors 212.0

H-bond Acceptors 204.0

Rotatable Bonds 477.0

Heavy Atoms 1033.0

Ring Count 25.0

Amide Bonds 139.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0092677 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted N-linked glycosylation of asparagine residues at positions 15 and 19; predicted disulphide bonf formation between cysteine resdiues at positions 38 and 51, 46 and 62, and 64 and 73

Bio-Activity Profile

Function

Immunomodulatory Signaling peptide

Targetepidermal growth factor receptor (Human)