Peptide Database

Peptide NameTachystatin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC196H299N59O55S5

DescriptionStandard

        YSRCQLQGFNCVVRSYGLPTIPCCRGSYFPGSTYGRCQRP
    

Molecular Weight4522.16 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.42

Charge Density (pH 7.0) 0.1177

GRAVY Index-0.40

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index32.80

Aliphatic Index 43.75

Aromaticity 0.1500

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1847.22

LogP -22.42

H-bond Donors 71.0

H-bond Acceptors 65.0

Rotatable Bonds 137.0

Heavy Atoms 315.0

Ring Count 10.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143503 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyTachystatin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity3 μg/mL

MethodIC50

RECORD: Rec_0158861 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyTachystatin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas pastoris

Activity0.5 μg/mL

MethodIC50

RECORD: Rec_0177948 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyTachystatin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity4.2 μg/mL

MethodIC50

RECORD: Rec_0376964 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

RECORD: Rec_0417381 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyTachystatin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity25 μg/mL

MethodIC50