Peptide Database

Peptide NameBeta-defensin 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC280H465N87O80S8

DescriptionStandard

        SQFLCHLVRKKCAGQLTALGQRSDSYICARKGGTCNLSPCPLYSRIEGTCYKGKAKCCIR
    

Molecular Weight6586.74 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)8.46

Net Charge (pH 7.4) 8.07

Charge Density (pH 7.0) 0.1411

GRAVY Index-0.25

Hydrophobic Moment 0.43

Boman Index-0.11

Instability Index42.55

Aliphatic Index 70.00

Aromaticity 0.0667

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2726.43

LogP -32.35

H-bond Donors 106.0

H-bond Acceptors 98.0

Rotatable Bonds 222.0

Heavy Atoms 455.0

Ring Count 7.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069439 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyDefensin

Tax ID9925

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal