Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC343H528N78O90S10

DescriptionStandard

        MKPLLIVFVFLIFWDPALAGLNPISSEMYKKCYGNGICRLECYTSEMLVGYCMFKLECCVKGNPDP
    

Molecular Weight7504.98 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-0.55

Net Charge (pH 7.4) -0.88

Charge Density (pH 7.0) -0.0084

GRAVY Index0.42

Hydrophobic Moment 0.52

Boman Index0.24

Instability Index21.21

Aliphatic Index 91.52

Aromaticity 0.1364

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2633.57

LogP -13.80

H-bond Donors 94.0

H-bond Acceptors 100.0

Rotatable Bonds 240.0

Heavy Atoms 521.0

Ring Count 15.0

Amide Bonds 68.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0033277 VERIFIED: NO

Provenance & Taxonomy

OrganismPteropus alecto [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence