Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC363H584N96O88S7

DescriptionStandard

        MKLLLLTLAILLLLSQLTPGDTQKCWNLHGRCRQKCFKKEKVYVYCTNGKHCCVKPKYQPKEKPWLF
    

Molecular Weight7925.57 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)9.61

Net Charge (pH 7.4) 9.18

Charge Density (pH 7.0) 0.1434

GRAVY Index-0.29

Hydrophobic Moment 0.43

Boman Index-0.05

Instability Index11.50

Aliphatic Index 90.15

Aromaticity 0.1045

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2980.00

LogP -18.58

H-bond Donors 108.0

H-bond Acceptors 107.0

Rotatable Bonds 266.0

Heavy Atoms 554.0

Ring Count 15.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198919 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic