Peptide Database

Peptide NameBrevinin-2LTc antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC365H589N89O115S6

DescriptionStandard

        MFTMKKSLLFLFFLGTISLSFCEEERGADEDDEVEMTEEEKRGVLDTFKDVAIGVAKGAGTGVLKALLCKLDKSC
    

Molecular Weight8256.50 Da

Isoelectric Point (pI)4.62

Net Charge (pH 7.0)-5.51

Net Charge (pH 7.4) -5.80

Charge Density (pH 7.0) -0.0734

GRAVY Index0.06

Hydrophobic Moment 0.70

Boman Index0.07

Instability Index24.75

Aliphatic Index 88.40

Aromaticity 0.0800

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3290.25

LogP -27.81

H-bond Donors 117.0

H-bond Acceptors 116.0

Rotatable Bonds 290.0

Heavy Atoms 575.0

Ring Count 6.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402302 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana latouchii [Animal]

FamilyBrevinin

Tax ID156873

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal