Peptide Database

Peptide NameSperm-associated antigen 11 variant E

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC409H645N117O118S9

DescriptionStandard

        MKALFLFAVLFCLVQGNSGDMPPGIRDVICLTQHGTCRLFFCHFGERKAEICSDPWNRCCLPSTEAEIKNKPETNDRNNKAKT
    

Molecular Weight9377.79 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.18

Charge Density (pH 7.0) 0.0195

GRAVY Index-0.29

Hydrophobic Moment 0.52

Boman Index-0.04

Instability Index38.38

Aliphatic Index 68.19

Aromaticity 0.0843

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3786.60

LogP -38.48

H-bond Donors 135.0

H-bond Acceptors 131.0

Rotatable Bonds 309.0

Heavy Atoms 653.0

Ring Count 15.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062684 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KR2/entry; https://bblserver.org.in/ampdb/

RECORD: Rec_0078691 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus dingo [Animal]

Tax ID286419

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

RECORD: Rec_0377077 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin