Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2339H3739N593O675S17

DescriptionStandard

        MFLWCVLVLLNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALVLVPDTGVMLSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVMSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQICPLVADSIADINPHLKTLNVLAKVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSLPSQDTDMLYIGVSAFTINSAGFVYNRAGALHLYITDDMIPSGSPIRLNTKTFGAFIPQIEKMYPGLMMKLLVETVKEPIVTFEPNNMTVQASSTVTAYAIQPNSTLSPLFVLNLEVSVSTHIYVTELKLAGNVTLNKINMSLAKSYVGPFQVTSLDNIFTIVLKFAVIPKVNARLQEGYPLPAIGKMQLVNSQLKVLKDYLLIGTDVQFTG
    

Molecular Weight51512.38 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)6.01

Net Charge (pH 7.4) 5.34

Charge Density (pH 7.0) 0.0127

GRAVY Index0.23

Hydrophobic Moment 0.72

Boman Index0.19

Instability Index29.40

Aliphatic Index 106.89

Aromaticity 0.0825

Extinction Coeff. Reduced 41830.00

Extinction Coeff. Oxidized 41955.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128024 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria