Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC543H877N149O164S4

DescriptionStandard

        PDLTGHEKFALGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIRNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAMFSTPLDNAGPASISLTSCQTTSGDVDIKLNGKT
    

Molecular Weight12244.93 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.04

Hydrophobic Moment 0.58

Boman Index0.12

Instability Index22.36

Aliphatic Index 94.91

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4998.70

LogP -55.91

H-bond Donors 177.0

H-bond Acceptors 174.0

Rotatable Bonds 404.0

Heavy Atoms 860.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0420847 VERIFIED: NO

Provenance & Taxonomy

OrganismOenanthe oenanthe [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria