Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC550H873N151O164S10

DescriptionStandard

        MTFLMLTLIMCGLLSQLVRAAWSVPKCWNNEGHCRRRCLDTERYKLLCKNKVSCCIPIRKTYDTPPQTEPPLINNIHNITIDTGTWKPASPGLNDEITFGDSDSEENFIT
    

Molecular Weight12545.38 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0034

GRAVY Index-0.31

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index64.03

Aliphatic Index 81.55

Aromaticity 0.0727

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5060.02

LogP -50.04

H-bond Donors 180.0

H-bond Acceptors 176.0

Rotatable Bonds 407.0

Heavy Atoms 875.0

Ring Count 21.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275092 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Tax ID10141

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence