MYP_134831
Temporin L[Pro3,DLeu9,Nle10](TL6)
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Antiviral
▸
Anti-Coronavirus
▸
Antiviral
▸
Anti-Herpesvirus
▸
Antiviral
▸
Antiviral
▸
Anti-Paramyxovirus
▸
cross
Antiviral
▸
Anti-Paramyxovirus
▸
Anti-HPIV
▸
cross
Antiviral
▸
Antiviral mechanism
▸
Membrane / Ion-channel modulation
▸
Sodium channel modulation
▸
Sodium channel inhibitor
Membrane / Ion-channel modulation
▸
Sodium channel modulation
▸
Sodium channel inhibitor
cross
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Toxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
FVPWFSKFLXRIL
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0318003
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Hydroxyproline, C- terminal NH2, small case letters are D amino acids at 10; Hydroxyproline, C- terminal NH2, small case letters are D amino acids
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
[Refer Pubmed ID 35216177: HSV-1 (
11.74 μM
IC50
RECORD: Rec_0318610
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
The 'X' at position 10 is 2-aminoindane-2-carboxylic acid
Bio-Activity Profile
Antimicrobial
Cytotoxic
RECORD: Rec_0320053
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Pentadecanoic acid
Amidation
The 'X' at position 10 is norleucine
Bio-Activity Profile
Antimicrobial
Cytotoxic
Vero cells:CC50>100
RECORD: Rec_0320775
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
The 'X' at position 10 is norleucine
Bio-Activity Profile
Antimicrobial
SARS-CoV-2:inhibition of replication in Vero cells
0.53 μM
IC50
RECORD: Rec_0322196
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
The 'X' at position 10 is 2-aminoindane-2-carboxylic acid
Bio-Activity Profile
Antimicrobial
HPIV-3:inhibition of replication in Vero cells
33.83 μM
IC50
Showing 5 records on this page · Page 36 of 49