MYP_134831
Temporin L[Pro3,DLeu9,Nle10](TL6)
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Antiviral
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Anti-Coronavirus
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Antiviral
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Anti-Herpesvirus
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Antiviral
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Antiviral
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Anti-Paramyxovirus
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cross
Antiviral
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Anti-Paramyxovirus
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Anti-HPIV
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cross
Antiviral
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Antiviral mechanism
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Membrane / Ion-channel modulation
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Sodium channel modulation
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Sodium channel inhibitor
Membrane / Ion-channel modulation
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Sodium channel modulation
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Sodium channel inhibitor
cross
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
FVPWFSKFLXRIL
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0292503
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
2-aminoindane-2-carboxylic acid (Aic), C- terminal NH2, small case letters are D amino acids at 10; 2-aminoindane-2-carboxylic acid (Aic), C- terminal NH2, small case letters are D amino acids
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
[Refer Pubmed ID 28863356: Bacillus megaterium Bm11 (
6.25 μM
MIC
RECORD: Rec_0294038
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
The 'x' at position 10 is D-hydroxyproline (Hyp)
Bio-Activity Profile
Antimicrobial
SARS-CoV-2:inhibition of replication in Vero cells
50 μM
IC50
RECORD: Rec_0296169
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Palmitic acid
Amidation
The 'X' at position 10 is norleucine
Bio-Activity Profile
Antimicrobial
Measles virus(MeV):inhibition of MeV replication in VERO/hSLAM cells
39.4 μM
IC50
RECORD: Rec_0298320
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
The 'X' at position 10 is norleucine
Bio-Activity Profile
Antimicrobial
HCoV-OC43:inhibition of replication in Vero cells
0.97 μM
IC50
RECORD: Rec_0300198
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Palmitic acid
Amidation
The 'X' at position 10 is norleucine
Bio-Activity Profile
Antimicrobial
HSV-1:inhibition of HSV-1 replication in Vero cells
3.13 μM
IC50
Showing 5 records on this page · Page 33 of 49