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MYP_134752
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Basic Information
Cholecystokinin-33
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
33 amino acids
C165H259N49O49S3
Standard
Sequence
KAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDF
Physicochemical Analysis
3809.32 Da
8.50
0.85
0.59
0.0257
-0.75
0.60
-0.15
67.49
59.09
0.0909
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1595.68
-16.12
56.0
54.0
126.0
266.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039029 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Cholecystokinin
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
27:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation
CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Mammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min
RECORD: Rec_0078697 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 36.4%, C 63.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0130488 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Gastrin/cholecystokinin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr27 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
Evidence URLhttps://www.uniprot.org/uniprotkb/CCKN_RAT/entry
RECORD: Rec_0410403 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal] [Animal]; Sus scrofa [Animal]
10116;9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone