Peptide Database

Peptide NameSLAY-screened peptide P3675

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC42H71N11O17S2

DescriptionStandard

        IDGTQMDACL
    

Molecular Weight1066.21 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.25

Net Charge (pH 7.4) -2.47

Charge Density (pH 7.0) -0.2248

GRAVY Index0.29

Hydrophobic Moment 0.03

Boman Index0.18

Instability Index56.17

Aliphatic Index 88.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 463.14

LogP -5.22

H-bond Donors 16.0

H-bond Acceptors 17.0

Rotatable Bonds 35.0

Heavy Atoms 72.0

Ring Count 0.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056548 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/