Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length583 amino acids

Chemical FormulaC2690H4269N813O853S10

DescriptionStandard

        MSGGDGIGHNSGAHSTGGVNGSSSGRGGSSSGGGNNPNSGPGWGTTHTPDGHDIHNYNPGEFGGGGHKPGGNSGNHSGGTGDGQTSGAAMAFGFPALVPAGAGGLAVTVSGDALAAAIADVLAVLKGPFKFGVWGIALYGILPTEIAKDDPRMMSKIVTSLPADAVTESPVSSLPLGQATISVTKRVTDVVKDERQHIAVVAGVPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNAPAMTALPRGVTDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQAEFNAAEKEKADADAALNVALESRKQKEQKAKDASDKLDKENKRNHPGKATGKGQPVGDKWLEDAGKEAGAPVPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPELSKQFIPGNKKRMSQGLAPRARNKDTVGGRRSFELHHDKPISQDGGVYDMDNIRVTTPKLHIDIHRGK
    

Molecular Weight61967.26 Da

Isoelectric Point (pI)7.87

Net Charge (pH 7.0)2.25

Net Charge (pH 7.4) 0.91

Charge Density (pH 7.0) 0.0039

GRAVY Index-0.67

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index38.25

Aliphatic Index 64.31

Aromaticity 0.0515

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063300 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. enterica serovar Weslaco [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Endonuclease Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli