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MYP_134718
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C35H46N6O8
Standard
Sequence
VYPFPG
Physicochemical Analysis
678.77 Da
5.49
-0.27
-0.48
-0.0445
0.35
0.22
0.54
80.53
48.33
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
211.47
0.31
6.0
8.0
14.0
49.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0092632 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
22 mmHg
SBP decrease
PaperAntihypertensive peptides from food proteins: a review. PMID22249830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22249830/
RECORD: Rec_0164742 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]
9913; 32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperEvaluation of the allergenicity of goat milk, cow milk, and their lactosera in a guinea pig model PMID19233776 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19233776/
RECORD: Rec_0228986 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
221 μM
IC50
PaperStructural analysis of new antihypertensive peptides derived from cheese whey protein by proteinase K digestion | Abubakar, A. et al. | DOI: 10.3168/jds.S0022-0302(98)75878-3 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0269303 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
221 μM
IC50
PaperAntihypertensive Peptides Specific to Lactobacillus helveticus Fermented Milk
RECORD: Rec_0271023 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
221.0
IC50
PaperAbubakar A., Saito T., Kitazawa H., Kawai Y., Itoh T.. Structural analysis of new antihypertensive peptides derived from cheese whey protein by proteinase K digestion. J.Dairy Sci., 81(12) 3131-3138(1998).
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