Peptide Database

Peptide NameRNS2_NICAL

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length214 amino acids

Chemical FormulaC1114H1717N295O320S16

DescriptionStandard

        DKQAFWKDEYVKHGTCCSDKFDREQYFDLAMTLRDKFDLLSSLRNHGISRGFSYTVQNLNNTIKAITGGFPNLTCSRLRELKEIGICFDETVKNVIDCPNMSKSQLTSVFFILLCALSPIYGAFEYMQLVLTWPITFCRIKHCERTPTNFPKTCKPTNKGVMFPTIHGLWPDNHTTMLNYCDRSKPYNMFTDGKKKNDLDERWPDLTKTKFDSL
    

Molecular Weight24875.37 Da

Isoelectric Point (pI)8.63

Net Charge (pH 7.0)5.11

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.0239

GRAVY Index-0.46

Hydrophobic Moment 0.61

Boman Index-0.05

Instability Index29.17

Aliphatic Index 68.32

Aromaticity 0.1215

Extinction Coeff. Reduced 32430.00

Extinction Coeff. Oxidized 33055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0039114 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana alata [Plant]

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme