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MYP_134650
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Basic Information
Cathelicidin-BF (Cathelicidin-related protein; Snakes, reptiles, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C176H290N48O35
Standard
Sequence
KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF
Physicochemical Analysis
3638.49 Da
11.79
10.75
10.54
0.3585
-0.54
0.90
-0.26
9.34
71.33
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1387.28
-6.76
50.0
46.0
129.0
259.0
7.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021106 VERIFIED: NO
Provenance & Taxonomy
Elapid snake [Animal]; Animalia [Animal]
Cathelicidin
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0025521 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecium
150 μg/mL
MIC
PMID18795096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0026503 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0027367 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0034249 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. aureus 08032810
100 μg/mL
MIC
PMID18795096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
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