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MYP_134650
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Basic Information
Cathelicidin-BF (Cathelicidin-related protein; Snakes, reptiles, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C176H290N48O35
Standard
Sequence
KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF
Physicochemical Analysis
3638.49 Da
11.79
10.75
10.54
0.3585
-0.54
0.90
-0.26
9.34
71.33
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1387.28
-6.76
50.0
46.0
129.0
259.0
7.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0228568 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC2002
4.7 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0245852 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli 08A866 IS/DR
0.6 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0250965 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus 08032712 IS/DR
100 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0259514 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
400000 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18795096/ PMID18795096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0259746 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa Clinical strains
16 μg/mL
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37356
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